Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-basedPROTAClinker can be used in the synthesis ofPROTACs^[1].

PROTAC technology employs small molecules that recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases is reported. Boc-C1-PEG2-C4-Cl is designated as 6-2-2^[1].

294.81

Liquid

C₁₄H₂₇ClO₄

1835705-53-7

Room temperature in continental US; may vary elsewhere.

DMSO : ≥ 50 mg/mL(169.60 mM)

*"≥" means soluble, but saturation unknown.

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。