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Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride图片
CAS NO:1416771-72-6
包装与价格：
包装价格(元)
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride 是一种可降解 (cleavable) 的 PEG 的ADC linker，可用于合成抗体偶联药物 (ADC)。Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride 也是一种PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。
生物活性

Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is acleavablePEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs[1][2].

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

分子量

373.78

Formula

C13H24ClNO9

CAS 号

1416771-72-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.