Articaine (Hoe-045 free base) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-qB activation and theNLRP3inflammasome pathway^[1][2][3].

NF-qB, NLRP3, sodium channel^[2][3]

284.37

C₁₃H₂₀N₂O₃S

23964-58-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.