Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor ofCaMKIIwith anIC₅₀of 40 nM.

IC50: 40 nM (CaMKII)^[1].

It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC₅₀of 40 nM, which is active in the presence or absence of Ca²⁺/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used^[1].

1497.74

C₆₄H₁₁₆N₂₂O₁₉

167114-91-2

Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu

KKALRRQEAVDAL

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.