Calcium channel-modulator-1 is acalcium channelmodulator; blocks aortic contraction with anIC₅₀of 0.8 μM.

IC50: 0.8 μM (Aortic contraction)^[1]

Oral administration of Calcium channel-modulator-1 (20 mg/kg) causes a 35-37% decrease in systolic blood pressure in spontaneously hypertensive rats. However, iv administration of Calcium channel-modulator-1 to anesthetized spontaneously hypertensive rats causes a decrease in blood pressure which was more pronounced and long-lasting than that of nifedipine^[1].

579.45

C₂₆H₂₄Cl₂N₂O₇S

136941-70-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.