EGFR-IN-55

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EGFR-IN-55

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2057423-46-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

EGFR-IN-55 (Compound 8a) 是一种有效的EGFR抑制剂，对EGFR^WT和EGFR^L858R/T790M的IC₅₀值分别为 70 nM 和 3.9 nM。EGFR-IN-55 阻滞 NCI-H1975 细胞 G0/G1 期，具有抗癌活性。

生物活性

EGFR-IN-55 (Compound 8a) is a potentEGFRinhibitor withIC₅₀values of 70 nM and 3.9 nM againstEGFR^WTandEGFR^L858R/T790M, respectively. EGFR-IN-55 arrests NCI-H1975 cells in G0/G1 phase and shows anticancer activity^[1].

IC₅₀& Target

EGFR^L858R/T790M

3.9 nM (IC₅₀)

EGFR^WT

70 nM (IC₅₀)

分子量

526.42

Formula

C₂₅H₂₅Cl₂N₇O₂

CAS 号

2057423-46-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.