EGFR-IN-52

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EGFR-IN-52

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

454436-75-0

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

EGFR-IN-52 (Compound 4) 是一种有效的EGFR抑制剂，对EGFR 、EGFR L858R-TK和EGFR T790M-TK的IC₅₀值分别为 0.358、86.02 和 432.67 μM。EGFR-IN-52 对癌细胞具有毒性，诱导细胞凋亡 (apoptosis)。

生物活性

EGFR-IN-52 (Compound 4) is a potentEGFRinhibitor withIC₅₀values of 0.358, 86.02 and 432.67 μM againstEGFR,EGFRL858R-TKandEGFRT790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity againstcancercell lines and inducesapoptosis^[1].

IC₅₀& Target

EGFR

0.358 μM (IC₅₀)

EGFR^L858R

86.02 μM (IC₅₀)

EGFR^T790M

432.67 μM (IC₅₀)

分子量

382.44

Formula

C₁₉H₁₈N₄O₃S

CAS 号

454436-75-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.