Lavendustin C

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Lavendustin C

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

125697-93-0

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品名称

N-(2,5-二羟基苄基)-5-氨基水杨酸

产品介绍

Lavendustin C 是一种有效的 Ca²⁺钙调蛋白依赖性激酶 II (CaMK II) 抑制剂，IC₅₀为 0.2 μM。Lavendustin C 抑制EGFR相关酪氨酸激酶 (IC₅₀=0.012 μM) 和pp60^c-src(+)激酶 (IC₅₀=0.5 μM)。

生物活性

Lavendustin C is a potentCa²⁺calmodulin-dependent kinase II (CaMK II)inhibitor with anIC₅₀of 0.2 μM. Lavendustin C inhibitsEGFR-associated tyrosine kinase (IC₅₀=0.012 μM) andpp60^c-src(+)kinase (IC₅₀=0.5 μM)^[1]^[2].

IC₅₀& Target^[1]^[2]

CaMK II

0.2 μM (IC₅₀)

EGFR

0.012 μM (IC₅₀)

体外研究
(In Vitro)

Lavendustin C (Compound 5) shows potent inhibitory activity, and it may be the core structure responsible for inhibition of tyrosine kinase^[1].
Lavendustin C (10-150 μM) inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation^[3].

分子量

275.26

Formula

C₁₄H₁₃NO₅

CAS 号

125697-93-0

中文名称

N-(2,5-二羟基苄基)-5-氨基水杨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.