COX-2-IN-14 (compound 2a) is a potent and selectiveCOX-2(cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site ofCOX-2co-crystal. COX-2-IN-14 exhibits a high level ofin vivoanti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice^[1].

386.36

C₁₈H₁₈N₄O₆

2428387-48-6

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