Phenidone, an orally active dual inhibitor ofcyclooxygenase (COX)andlipoxygenase(LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat^[1][2]. Phenidone is used as a photographic developer^[3].

Phenidone significantly inhibits the increases in COX-1/-2 and 5-LOX in the spinal cords of rats with experimental autoimmune encephalomyelitis (EAE)^[1].

Phenidone inhibits the formation of vascular lipoxygenase products and to reduce blood pressure in the AII-dependent renovascular hypertensive rat^[2].

162.19

Solid

C₉H₁₀N₂O

92-43-3

菲尼酮

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

DMSO : 100 mg/mL(616.56 mM;Need ultrasonic)

H₂O : 3.33 mg/mL(20.53 mM;ultrasonic and warming and heat to 60℃)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。