(R)-Methanandamide (AM-356), an analog of the endocannabinoid ligand Anandamide, is a potentCB1agonist with aK_iof 20 nM. (R)-Methanandamide also activatesvanilloid (TRPV1) receptors^[1][2].

The endogenous cannabinoid (R)-Methanandamide exerts differential anti- and pronociceptive effects by activating both cannabinoid (CB1) and vanilloid (TRPV1) receptors of nociceptive primary afferents^[2].

361.56

C₂₃H₃₉NO₂

157182-49-5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.