Aclerastide

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Aclerastide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

227803-63-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品名称

阿勒司肽
DSC-127
NorLeu3-A(1-7)

产品介绍

Aclerastide (DSC-127) 是一种血管紧张素受体激动剂。Aclerastide 也是血管紧张素 II 的肽类似物。Aclerastide 可用于糖尿病溃疡组织再生的研究。

生物活性

Aclerastide (DSC-127) is anangiotensin receptoragonist. Aclerastide also is a peptide analog of angiotensin II. Aclerastide can be used for the research of tissue regeneration in diabetic ulcers^[1]^[2].

体内研究
(In Vivo)

Aclerastide (0.1 mg/wound; day for 5 days) shows superior efficacy in the db/db mouse model of wound healing^[1].
Aclerastide (topically administered; 100 μL; once a day; for 14 days) elevates levels of reactive oxygen species and of active MMP-9^[2].

Animal Model:	db/dbmice^[2]
Dosage:	100 μL
Administration:	Topically administered, once a day, for 14 days
Result:	Upregulated reactive oxygen species during inflammation. Increased the levels of the detrimental active MMP-9 in diabetic wounds.

Clinical Trial

分子量

913.03

Formula

C₄₂H₆₄N₁₂O₁₁

CAS 号

227803-63-6

Sequence Shortening

DR-{Nle}-YIHP

中文名称

阿勒司肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.