[DPro10] Dynorphin A (1-11), porcine, a N-Alkylated derivative, is a potentκ-opioid receptoragonist with aK_ivalue of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine has analgesic property^[1][2].

[DPro10] Dynorphin A (1-11), porcine has inhibition of adenylyl cyclase activity in k-opioid receptor-expressing CHO cells with an IC₅₀value of 0.12 nM^[1].

[DPro10] Dynorphin A (1-11), porcine (ICV) has analgesic effects involving thermal cutaneous (tail-flick) and chemical visceral (AcOH-induced writhing) stimuli, in which mu and kappa receptors are known to be activated differentially^[2].

1362.63

C₆₃H₁₀₃N₂₁O₁₃

94596-26-6

YGGFLRRIR-{d-Pro}-K

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.