5-HT2 antagonist 1 is a potent antagonist of5-HT2 receptor, with weakα1 adrenoceptorblocking activity.

5-HT2 antagonist 1 shows 45%, 88%, 93% inhibition of 10 μM erotonin-induced contraction at 10 nM, 100 nM, 1000 nM, respectively, in guinea pig mesentcric artery. 5-HT2 antagonist 1 causes 1% and 10% inhibition of 10 μM norepinephrine-induced contraction at 10 and 100 nM, respectively, in guinea pig aorta^[1].

400.49

C₂₂H₂₉FN₄O₂

191592-09-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.