Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combinedCa²⁺/5-HT₂antagonist on thrombus formation in vivo and on platelet aggregation in vitro.

Serotonin-induced platelet aggregation in dog platelet-rich plasma (PRP) in vitro is most potently inhibited by Nexopamil (IC₅₀81 nM)^[1].

Nexopamil (0.05 mg/kg) completely abolishes cyclic flow reductions (CFRs) during the first 30 min after application without significantly altering hemodynamics^[1].

404.59

C₂₄H₄₀N₂O₃

116759-35-4

奈索帕米

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