Antitumor agent-72

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Antitumor agent-72

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Antitumor agent-72 是一种有效的抗癌剂。Antitumor agent-72 具有抗癌活性，并通过激活 caspase-3 和裂解 PARP 诱导细胞凋亡 (apoptosis)。Antitumor agent-72 可用于癌症研究。

生物活性

Antitumor agent-72 (compound 6w) is a potent anticancer agent. Antitumor agent-72 has anticancer activity and inducesapoptosisthrough activation of caspase-3 and cleavage ofPARP. Antitumor agent-72 can be used forcancerresearch^[1].

体外研究
(In Vitro)

Antitumor agent-72 (compound 6w) (0-10 μM; 72 h; BxPC3, PC3 and MCF7 cells) has anticancer activity and inhibits cell viability in a dose-dependent manner^[1].
Antitumor agent-72 (compound 6w) (0-10 μM; 24 h; BxPC3 cells) induces apoptosis through activation of caspase-3 and cleavage of PARP^[1].

Cell Viability Assay^[1]

Cell Line:	BxPC3, PC3 and MCF7 cells
Concentration:	0, 0.03, 0.1, 0.3, 1, 3 and 10 μM
Incubation Time:	72 hours
Result:	Inhibited cell viability in BxPC3, PC3 and MCF7 cells with IC₅₀values of 0.47 μM, 2.68 μM and 1.82 μM, respectively.

Western Blot Analysis^[1]

Cell Line:	BxPC3 cells
Concentration:	0, 0.1, 0.3, 1, 3 and 10 μM
Incubation Time:	24 hours
Result:	Increased caspase-3 activation and PARP cleavage in BxPC3 cells.

分子量

467.90

Formula

C₂₅H₂₂ClNO₆

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.