ARTD10/PARP10-IN-2

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ARTD10/PARP10-IN-2

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1708103-69-8

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

ARTD10/PARP10-IN-2 (compound 19) 是一种强效、非选择性的PARP抑制剂。ARTD10/PARP10-IN-2 靶向单 ADP 核糖转移酶 (ARTD10/PARP10) 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1)，IC₅₀分别为 2.0 μM，和 9.7 μM。

生物活性

ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selectivePARPinhibitor, targeting to mono-ADP-ribosyltransferasesARTD10/PARP10and poly(ADP-ribose) polymerase-1ARTD1/PARP1withIC₅₀s of 2.0 μM, and 9.7 μM, respectively^[1].

IC₅₀& Target^[1]

ARTD1/PARP1

9.7 μM (IC₅₀)

ARTD10/PARP10

2.0 μM (IC₅₀)

ARTD8/PARP14

>20 μM (IC₅₀)

ARTD7/PARP15

>20 μM (IC₅₀)

分子量

247.25

Formula

C₁₂H₁₃N₃O₃

CAS 号

1708103-69-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.