BAY-6035 is a potent, selective and substrate-competitive inhibitor ofSMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with anIC₅₀of 88 nM^[1].

BAY-6035 inhibits in vitro methylation of MEKK2 peptide with an IC₅₀of 88 nM and has more than 100-fold selectivity over other histone methyltransferases^[1].
BAY-6035 inhibits the methylation of MEKK2 in cells with an IC₅₀of 70 nM^[1].

396.48

Solid

C₂₂H₂₈N₄O₃

2247890-13-5

Room temperature in continental US; may vary elsewhere.

DMSO : 100 mg/mL(252.22 mM;Need ultrasonic)

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