CHK1-IN-4 (Compound 3) is a potentcheckpoint kinase 1 (chk1)inhibitor, and potently inhibitschk1phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity^[1].

CHK1-IN-4 (Compound 3) (40 mg/kg, IV, twice a week) alone enhances anti-tumor growth activity of CPT1 in the tumor model^[1].

444.29

C₁₈H₁₈BrN₇O₂

2120398-41-4

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