Aurora kinaseinhibitor-10 (Compound 6c) is an orally activeAurora Binhibitor with anIC₅₀of 8 nM.Aurora kinaseinhibitor-10 shows antitumor activity^[1].

Aurora kinase inhibitor-10 (Compound 6c) shows antiproliferation activity with IC₅₀values of 0.57 ± 0.23, 0.42 ± 0.20, 0.69 ± 0.30, 3.97 ± 0.67 and 1.53 ± 0.52 μM against MCF-7, MDA-MB 231, SkoV3, A375 and A549, respectively^[1].

546.47

C₂₁H₁₉F₅N₆O₄S

2417228-90-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.