ATR-IN-14

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ATR-IN-14

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2765785-88-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

ATR-IN-14 (化合物 1) 是一种有效的ATR激酶抑制剂。ATR-IN-14 抑制 ATR 信号通路下游 CHKI 蛋白磷酸化，25 nM 时抑制率为 98.03%。ATR-IN-14 在 LoVo 细胞中表现出良好的抗癌活性，IC₅₀为 64 nM。

生物活性

ATR-IN-14 (compound 1) is a potentATRkinase inhibitor. ATR-IN-14 inhibitsATRsignaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with anIC₅₀of 64 nM^[1].

IC₅₀& Target

ATR

分子量

393.42

Formula

C₂₀H₂₀FN₇O

CAS 号

2765785-88-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.