T01-1

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T01-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2356229-14-4

包装与价格：

产品介绍

T01-1 是一种抗癌剂 (喜树碱衍生物)，具有较好的抗肿瘤细胞增殖活性。

生物活性

T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity^[1].

体外研究
(In Vitro)

T01-1 (0-50 nM; 3 days) anti-proliferative activity in HCC1806 cells^[1].

Cell Proliferation Assay^[1]

Cell Line:	HCC1806 cells
Concentration:	0-50 nM
Incubation Time:	3 days
Result:	Inhibited cell proliferation with an EC₅₀value of 6.7 nM.

体内研究
(In Vivo)

T01-1 (1 mg/kg; i.v.; single) shows T_1/2values of 2.78 and 1.97 h in female and male rats, respectively^[1].

Animal Model:

Sprague Dawley rat (half male and half female)^[1].

Dosage:

1 mg/kg

Administration:

Intravenous injection; single

Result:

1.19Pharmacokinetic Parameters of T01-1 in Sprague Dawley rat^[1].

分子量

511.59

性状

Solid

Formula

C₂₆H₂₉N₃O₆S

CAS 号

2356229-14-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)