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(S)-Rasagiline(TVP1022)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(S)-Rasagiline(TVP1022)图片
CAS NO:185517-74-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议

产品介绍
(S)-雷沙吉兰 (TVP1022) (TVP1022) 是雷沙吉兰相对无活性的 S-对映异构体形式。
Cas No.185517-74-2
别名(S)-雷沙吉兰; TVP1022; S-PAI
Canonical SMILESC#CCN[C@H]1CCC2=CC=CC=C21
分子式C12H13N
分子量171.24
溶解度DMSO : ≥ 38 mg/mL (221.91 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-Rasagiline (TVP1022) is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69. [2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.