WEHI-539

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WEHI-539

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1431866-33-9

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

WEHI-539 是一种选择性的Bcl-XL抑制剂，IC₅₀为 1.1 nM。

生物活性

WEHI-539 is a selective inhibitor ofBcl-XLwith anIC₅₀of 1.1 nM.

IC₅₀& Target

Bcl-xL

1.1 nM (IC₅₀)

体外研究
(In Vitro)

WEHI-539 is a selective inhibitor of Bcl-X_L. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells^[2].

分子量

583.72

Formula

C₃₁H₂₉N₅O₃S₂

CAS 号

1431866-33-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.