Resolvin D1 甲酯（RvD1 甲酯）是 Resolvin D1 的甲酯。
| Cas No. | 937738-63-1 |
| 别名 | RvD1 methyl ester |
| Canonical SMILES | CC/C=C\C[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)C/C=C\CCC(OC)=O |
| 分子式 | C23H34O5 |
| 分子量 | 390.5 |
| 溶解度 | DMF: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.05 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid. |
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