Mal-PEG2-Val-Cit-PAB-OH is acleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as aPROTAClinkerthat can be used in the synthesis ofPROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

618.68

C₂₉H₄₂N₆O₉

2055041-38-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.