DBCO-NHS ester 3

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DBCO-NHS ester 3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1393350-27-0

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

DBCO-NHS ester 3 (Compound 12) 是一种用于制备抗体偶联药物 (ADC) 的可降解 linker。DBCO-NHS ester 3 是一种二苯基环辛酮 (DBCO) 衍生物，通过 MeOND 和 DIBAC 的羧酸部分被 N-羟基琥珀酰亚胺活化而获得的。

生物活性

DBCO-NHS ester 3 (Compound 12) is acleavablelinker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)^[1]^[2].

IC₅₀& Target^[1]

Cleavable

分子量

416.43

Formula

C₂₄H₂₀N₂O₅

CAS 号

1393350-27-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.