| CAS NO: | 38304-91-5 |
| 包装 | 价格(元) |
| 500mg | 电议 |
| 1g | 电议 |
| Cas No. | 38304-91-5 |
| 别名 | 米诺地尔; U10858 |
| 化学名 | 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine |
| Canonical SMILES | C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O |
| 分子式 | C9H15N5O |
| 分子量 | 209.25 |
| 溶解度 | Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3]. Minoxidil (1-00 μM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined (from 1 μM to 100 μM)[1]. Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%)[1]. References: |
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