THIP hydrochloride (Lu 02-030 hydrochloride) 是 GABAA 受体的有效激动剂和 GABAC 受体的拮抗剂 (IC50=25 μM)。
| Cas No. | 85118-33-8 |
| 别名 | GAB氧杂DOL盐酸盐 |
| 化学名 | 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride |
| Canonical SMILES | O=C1NOC2=C1CCNC2.Cl |
| 分子式 | C6H8N2O2.HCl |
| 分子量 | 176.6 |
| 溶解度 | DMF: 0.1 mg/ml,DMSO: 20 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | 4℃, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |