Palbociclib D8 (PD 0332991 D8) is a deuterium labeled Palbociclib. Palbociclib is a selective and orally activeCDK4andCDK6inhibitor withIC₅₀s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breastcancerresearch^[1].

455.58

Solid

C₂₄H₂₁D₈N₇O₂

1628752-83-9

帕布昔利布 d8

Room temperature in continental US; may vary elsewhere.

H₂O : 8.33 mg/mL(18.28 mM;ultrasonic and warming and adjust pH to 3 with HCl and heat to 80℃)

DMSO : 1 mg/mL(2.20 mM;ultrasonic and warming and heat to 60℃)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。