ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation^[1][2].

ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs^[3].
ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner^[4].
ATP promotes neutrophil chemotaxis in vitro^[4].

ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo^[4].
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo^[4].

555.79

C₁₀H₁₆Mg₂N₅O₁₃P₃

74804-12-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.