sEH/AChE-IN-4 (compound (+)-15) is a potent and BBB-penetrated dual inhibitor ofsEH(soluble epoxide hydrolase) andAChE(acetylcholinesterase), withIC₅₀values of 3.1 nM (hsEH), 1660 nM (hAChE), 179 nM (hBChE, human butyrylcholinesterase), 14.5 nM (msEH), and 102 nM (mAChE), respectively^[1].

IC₅₀: 3.1 nM (hsEH), 1660 ± 450 nM (hAChE), 179 ± 26 nM (hBChE), 14.5 nM (msEH), 102 ± 18 nM (mAChE)^[1]

670.16

C₃₅H₃₉ClF₃N₅O₃

2490589-12-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.