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Garenoxacin Mesylate hydrate(BMS284756(Mesylate hydrate))
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Garenoxacin Mesylate hydrate(BMS284756(Mesylate hydrate))图片
CAS NO:223652-90-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议

产品介绍
Garenoxacin (BMS284756) Mesylate hydrate 是一种具有口服活性的喹诺酮类抗生素，对多种革兰氏阳性和革兰氏阴性细菌、厌氧菌和苛求微生物具有广谱活性。
Cas No.223652-90-2
别名加雷沙星甲磺酸盐; BMS284756 Mesylate hydrate
Canonical SMILESO=C(C1=CN(C2CC2)C3=C(C=CC(C4=CC5=C([C@@H](C)NC5)C=C4)=C3OC(F)F)C1=O)O.CS(=O)(O)=O.O
分子式C24H26F2N2O8S
分子量540.53
溶解度DMSO : ≥ 30 mg/mL (55.50 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.

[1]. Waites KB, et al. In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother. 2003 Jan;47(1):161-5. [2]. Ince D, et al. Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone. Antimicrob Agents Chemother. 2002 Nov;46(11):3370-80. [3]. Zhao X, et al. Mutant prevention concentration of garenoxacin (BMS-284756) for ciprofloxacin-susceptible or -resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2003 Mar;47(3):1023-7.