| CAS NO: | 2622070-93-1 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 生物活性 | (Rac)-Etavopivat ((Rac)-FT-4202) is an isomer ofEtavopivat(HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies[1]. | ||||||||||||
| 体外研究 (In Vitro) | Etavopivat (20 μM, 4 h)可以改善人红细胞中血红蛋白-氧亲和力并降低了镰状点 (PoS)[1]。 | ||||||||||||
| 体内研究 (In Vivo) | Etavopivat(口服,3-22mg/kg,每天一次,5天)在 8 mg/kg和 22 mg/kg 的剂量下引起食蟹猴 2,3-DPG 和 ATP 的增加[1]。 | ||||||||||||
| 分子量 | 457.50 | ||||||||||||
| 性状 | Solid | ||||||||||||
| Formula | C22H23N3O6S | ||||||||||||
| CAS 号 | 2622070-93-1 | ||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| 储存方式 |
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