BAPTA tetrasodium is a selectivechelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca²⁺release from intracellular stores or influx via Ca²⁺-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibitphospholipaseCactivity independently of their role as Ca²⁺chelators^[1][2][3].

BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca²⁺]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells^[3].
BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca^2+[2].

564.36

Solid

C₂₂H₂₀N₂Na₄O₁₀

126824-24-6

BAPTA四钠盐水合物

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)