Ethacrynic acid D5 is a deuterium labeled Ethacrynic acid. Ethacrynic acid is a diuretic. Ethacrynic acid is an inhibitor ofglutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor ofNF-kB-signalingpathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operatedcalcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice^[1][2][3][4].

Glutathione S-transferases (GSTs)^[1]; NF-κB-signaling pathway^[2]; L-type voltage-dependent and store-operated calcium channel^[3]

308.17

C₁₃H₇D₅Cl₂O₄

1330052-59-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.