Antifungal agent 46 (compound 2f) is a potent antifungal agent. Antifungal agent 46 preventsRassignaling by inhibiting proteinfarnesyltransferase^[1].

Antifungal agent 46 (compound 2f) inhibits growth at 12.5 μM in biofilm assay, corresponding to a 2-fold higher MIC thanAmphotericin B(HY-B0221)^[1].

Antifungal agent 46 (compound 2f, 0.78 μM) inhibits FTase activityin vivo^[1].

565.43

C₂₆H₂₈BrF₃N₄O₂

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.