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Lenampicillin hydrochloride(KBT 1585 hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Lenampicillin hydrochloride(KBT 1585 hydrochloride)图片
CAS NO:80734-02-7
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议

产品介绍
Lenampicillin hydrochloride (KBT 1585 hydrochloride) (KBT 1585 hydrochloride) 是 Ampicillin 的口服活性前药，是一种有效的 β-内酰胺抗菌剂，可抑制细菌青霉素结合蛋白（转肽酶）。 Lenampicillin hydrochloride (KBT 1585 hydrochloride) 与 Ampicillin 相比具有改善的吸收和减少的副作用，用于化脓性皮肤和软组织感染的调查。
Cas No.80734-02-7
别名盐酸仑氨苄西林; KBT 1585 hydrochloride
Canonical SMILESO=C([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)OCC(OC4=O)=C(O4)C.Cl
分子式C21H24ClN3O7S
分子量497.95
溶解度Soluble in DMSO
储存条件Store at -20°C, sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.