| CAS NO: | 184776-51-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 184776-51-0 |
| Canonical SMILES | Lys-Lys-Ala-Leu-Leu-Ala-Leu-Ala-Leu-His-His-Leu-Ala-His-Leu-Ala-Leu-His-Leu-Ala-Leu-Ala-Leu-Lys-Lys-Ala |
| 分子式 | C132H228N38O27 |
| 分子量 | 2779.53 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | LAH4 is an antimicrobial peptide that strongly interacts with phospholipid membranes, exhibiting in vitro transfection efficiency. LAH4 exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities[1]. LAH4 mediates the transport of functional β-galactosidase, a large tetrameric protein of about 0.5 MDa, into the cell interior[2]. At acidic pH, LAH4 has exhibited a high tendency to interact strongly with and be adsorbed on anionic membrane[3]. [1]. Perrone B, et al. Lipid interactions of LAH4, a peptide with antimicrobial and nucleic acid transfection activities. Eur Biophys J. 2014 Nov;43(10-11):499-507. [2]. Moulay G, et al. Histidine-rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo. J Pept Sci. 2017 Apr;23(4):320-328. [3]. Islami M, et al. Study of orientation and penetration of LAH4 into lipid bilayer membranes: pH and composition dependence. Chem Biol Drug Des. 2014 Aug;84(2):242-52. |
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