| CAS NO: | 122479-08-7 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 122479-08-7 |
| 化学名 | (E)-4-(3-methoxy-6-((3-methoxybenzyl)imino)-5,6-dihydroimidazo[1,2-b]pyridazin-2-yl)aniline |
| Canonical SMILES | COC1=CC=CC(C/N=C2C=CC3=NC(C4=CC=C(N)C=C4)=C(OC)N3N\2)=C1 |
| 分子式 | C21H21N5O2 |
| 分子量 | 375.43 |
| 溶解度 | Soluble in ethanol or DMSO |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GBLD 345 is a potent agonist of benzodiazepine receptor. Benzodiazepine receptor is an allosteric modulatory site on GABAA receptor [1]. The GABAA receptor is a ligand-gated ion channel and activated by γ-aminobutyric acid (GABA). The GABAA receptor selectively permits Cl- through its pore and results in hyperpolarization of the neuron, which causes an inhibitory effect on neurotransmission. GBLD 345 is a potent benzodiazepine receptor agonist with IC50 value of 1 nM against diazepam. Reference: |
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