Nitidine chloride, a potentialanti-malariallead compound derived fromZanthoxylum nitidum(Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducingapoptosis, inhibitingSTAT3signaling cascade,DNAtopoisomerase1 and 2A,ERKandc-Src/FAKassociated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production viaMAPKandNF-kBpathway^{[1][2][3][4][5][6]}.

383.82

Solid

C₂₁H₁₈ClNO₄

13063-04-2

氯化两面针碱

• Alkaloids
• Isoquinoline Alkaloids

• Plants
• Rutaceae
• Zanthoxylum nitidum(Roxb.) DC.

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

DMSO : 2 mg/mL(5.21 mM;Need ultrasonic)

*Nitidine chloride is usually formulated as a suspension.

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。