CAS NO: | 1429617-90-2 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | 7rh (DDR1-IN-2) is a potent inhibitor ofdiscoidin domain receptor1(DDR1), with anIC50of 13.1 nM, and also less potently inhibitsDDR2, with anIC50of 203 nM. | ||||||||||||||||
IC50& Target | IC50: 13.1 nM (DDR1), 203 nM (DDR2), 414 nM (Bcr-Abl), 2500 nM (c-Kit)[1] | ||||||||||||||||
体外研究 (In Vitro) | 7rh (compound 1) is a potent inhibitor of DDR1, with an IC50of 13.1 nM, and less potently inhibits DDR2, with an IC50of 203 nM. 7rh also shows inhibitory activities against Bcr-Abl and c-Kit, with IC50s of 414 and 2500 nM, respectively[1]. | ||||||||||||||||
分子量 | 546.59 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C30H29F3N6O | ||||||||||||||||
CAS 号 | 1429617-90-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 62.5 mg/mL(114.35 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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