1-Dehydro-[10]-gingerdione

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

136826-50-1

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

1-Dehydro-[10]-gingerdione 通过靶向IKKβ的激活环直接抑制 IKKβ 活性，从而破坏用激动剂刺激的巨噬细胞中 IKKβ 催化的 IκBα 磷酸化。1-Dehydro-[10]-gingerdione 抑制 LPS (HY-D1056) 诱导的NF-κB转录活性。1-Dehydro-[10]-gingerdione 具有用于 NF-κB 相关炎症和自身免疫性疾病研究的潜力。

生物活性	1-Dehydro-[10]-gingerdione directly inhibitsIKKβactivity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS (HY-D1056)-inducedNF-κBtranscriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research^[1].
分子量	346.46
Formula	C₂₁H₃₀O₄
CAS 号	136826-50-1
结构分类	Phenols Monophenols
来源	Plants Zingiberaceae
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.