BACE-1 inhibitor 2 is a potent and CNS permeableBACE-1inhibitor with anIC₅₀of 1.5 nM in BACE-1 enzymatic assay^[1].

IC50: 1.5 nM (BACE-1)^[1]

BACE-1 inhibitor 2 inhibits Aβ42 production in human neuroblastoma cell lines with an IC₅₀of 3.5 nM^[1].

467.42

C₂₁H₂₁F₄N₅O₃

2563970-92-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.