Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of theNa⁺/H⁺exchanger (NHE-1).

NHE1^[1]

Blocking NHE-1 activity has been shown to decrease intracellular Na⁺and Ca²⁺overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent^[1].

369.84

C₁₁H₁₆ClN₃O₅S₂

187870-95-7

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.