Antitumor agent-84 (compound 21a) is aG-quadruplex(G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-84 has highly effective anti-tumor properties^[1].

Antitumor agent-84 稳定 c-MYC Pu24T，c-MYC Pu22，CKit1，CKit2，KRAS 和 G4 的 DNA 结构^[1]。
Antitumor agent-84 (1-10000 nM) 抑制肿瘤类器官和癌症激活的成纤维细胞 (CAF)，IC₅₀值分别为 161 和 2515 nM^[1]。

417.55

C₂₄H₃₁N₇

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.