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L-651,582
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
L-651,582图片
CAS NO:99519-84-3
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
L-651,582 (L-651582) 是一种非电压操作的钙通道和钙通道介导的信号通路的细胞抑制抑制剂。
Cas No.99519-84-3
别名5-氨基-1-(3,5-二氯-4-(4-氯苯甲酰基)苄基)-1H-1,2,3-三氮唑-4-甲酰胺,L-651582; CAI
化学名5-amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
Canonical SMILESClC1=CC(CN2N=NC(C(N)=O)=C2N)=CC(Cl)=C1C(C(C=C3)=CC=C3Cl)=O
分子式C17H12Cl3N5O2
分子量424.67
溶解度<42.47mg/ml in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carboxyamidotriazole (L 651582) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].

References:
[1]. Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229.
[2]. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.