| CAS NO: | 2068818-02-8 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 2068818-02-8 |
| Canonical SMILES | CC(C1=C(C(Cl)(Cl)Cl)N[B-](C2=CC=CC=C2)(C3=CC=CC=C3)[O+]=C1N)=O |
| 分子式 | C18H16BCl3N2O2 |
| 分子量 | 409.5 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs). Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355 |
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