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Sipatrigine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Sipatrigine图片
CAS NO:130800-90-7
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
Sipatrigine (619C89) 是一种神经保护剂，是一种谷氨酸释放抑制剂、电压依赖性钠通道和钙通道抑制剂，可穿透中枢神经系统。
Cas No.130800-90-7
别名西帕曲近,619C89; BW 619C89
化学名2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine
Canonical SMILESClC(C(C1=CN=C(N=C1N)N2CCN(C)CC2)=CC(Cl)=C3)=C3Cl
分子式C15H16Cl3N5
分子量372.68
溶解度<9.32mg/ml in ethanol;<37.27mg/ml in DMSO
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2].

References:
[1]. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.
[2]. Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.