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3-Oxocholic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3-Oxocholic Acid图片
CAS NO:2304-89-4
包装与价格：
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
3-氧代胆酸是一种氧代胆汁酸代谢物，也是 C. 胆酸的主要降解产物。
Cas No.2304-89-4
别名3-酮基-7ALPHA,12ALPHA-二羟基-5ALPHA-胆烷酸,3-Dehydrocholic Acid
化学名(5β,7α,12α)-7,12-dihydroxy-3-oxo-cholan-24-oic acid
Canonical SMILESO=C1CC[C@@]2(C)[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CCC(O)=O)C)([H])C1
分子式C24H38O5
分子量406.6
溶解度30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid in C. perfringens, a bacteria found in the intestines of mammals and in the environment.[1],[2] 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.[3]

References
[1]. Wahlstrom, A., Sayin, S.I., Marschall, H.-I., et al. Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metab. 24(1), 41-50 (2016).
[2]. Macdonald, I.A., Forrest, T.P., Costain, G.A., et al. Identification of 7α-, 12α-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens. J. Steroid Biochem. 9(4), 353-358 (1978).
[3]. Yan, K., Chen, W., Zhu, H., et al. The changes of serum metabolites in diabetic GK rats after ileal transposition surgery. Obes. Surg. 29(3), 882-890 (2019).